SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
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DOI: 10.1016/j.canlet.2021.07.035
Abstract: SGLT2 is overexpressed in various cancers, including pancreatic cancer. However, the mechanisms underlying the tumorigenic effects of SGLT2 in pancreatic cancer remain unclear. In this study, we demonstrated that SGLT2 inhibition significantly suppressed the growth… read more here.
Keywords: sglt2 promotes; hippo signaling; pancreatic cancer; hnrnpk ... See more keywords