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   Articles with "sglt2i" as a keyword



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SGLT2 Inhibitors and the Risk of Hospitalization for Fournier’s Gangrene: A Nested Case–Control Study

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recommendations! Published in 2020 at "Diabetes Therapy"

DOI: 10.1007/s13300-020-00771-8

Abstract: Introduction Based on post-marketing surveillance, concern has been raised that sodium–glucose cotransporter 2 inhibitors (SGLT2i) may increase the risk of necrotizing fasciitis of the perineum (Fournier’s gangrene, FG). As a result of the low incidence of… read more here.

Keywords: hospitalization; fournier gangrene; study; case control ... See more keywords
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Comparative effectiveness of SGLT2i versus GLP1-RA on cardiovascular outcomes in routine clinical practice.

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recommendations! Published in 2022 at "International journal of cardiology"

DOI: 10.1016/j.ijcard.2022.01.042

Abstract: BACKGROUND To investigate the comparative effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP1-RA) on cardiovascular outcomes in routine clinical practice, which have never been directly compared in head-to-head outcome… read more here.

Keywords: risk; cardiovascular outcomes; comparative effectiveness; glp1 cardiovascular ... See more keywords

Chronic cardiorenal syndrome: cardio-renal protective effect of SGLT2i

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recommendations! Published in 2025 at "Renal Failure"

DOI: 10.1080/0886022x.2025.2575921

Abstract: Abstract Objectives Chronic cardiorenal syndrome (types 2 and 4) arises from chronic dysfunction of either the heart or kidneys, leading to progressive deterioration of the other organ. The coexistence of cardiac and renal dysfunction significantly… read more here.

Keywords: non diabetic; chronic cardiorenal; cardiorenal syndrome; sglt2i ... See more keywords

The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis

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recommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"

DOI: 10.1080/17512433.2022.2102973

Abstract: ABSTRACT Objective To assess the association between the use of sodium–glucose cotransporter 2 inhibitor (SGLT2i) and the incidence of diabetic retinopathy (DR). Research design and methods PubMed, Medline, Embase, the Cochrane Central Register of Controlled… read more here.

Keywords: use sodium; association use; sglt2i; risk ... See more keywords

Real-life data on the tolerability of SGLT2 inhibitors in elderly patients with heart failure

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recommendations! Published in 2024 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehae666.1079

Abstract: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have demonstrated their effectiveness in improving the prognosis of heart failure. However, there is some hesitation in clinical practice to prescribe them to elderly patients due to a lack of… read more here.

Keywords: heart; patients heart; elderly patients; sglt2i ... See more keywords

4328Short-term effects of dapagliflozin versus canagliflozin on acute decompensated heart failure in patients with type 2 diabetes

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recommendations! Published in 2019 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehz745.0165

Abstract: The CANVAS program and DECLERE-TIMI 58 reported that SGLT2i had been demonstrated to reduce hospitalization for heart failure (HF) in type 2 diabetic mellitus (T2DM) patients with high cardiovascular disease risk. However, it remains unclear… read more here.

Keywords: heart; volume; cana; dapa ... See more keywords

Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular outcomes in patients with atrial fibrillation and type 2 diabetes mellitus

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recommendations! Published in 2023 at "Europace"

DOI: 10.1093/europace/euad122.048

Abstract: Abstract Funding Acknowledgements Type of funding sources: None. Background A sodium-glucose cotransporter-2 inhibitor (SGLT2i) improves clinical outcomes in patients with type 2 diabetes (T2DM) and cardiovascular disease. Also use of SGLT2i was associated with a… read more here.

Keywords: outcomes patients; glucose cotransporter; sglt2i; group ... See more keywords
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MO129COMPARATIVE EFFECTIVENESS OF SGLT2I VERSUS DPP4I ON CARDIOVASCULAR AND RENAL OUTCOMES IN ROUTINE-CARE SETTINGS

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recommendations! Published in 2021 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfab092.007

Abstract: While clinical trials have demonstrated the efficacy of SGLT2 inhibitors on preventing cardiovascular and renal damage, few studies have expanded this evidence to routine-care settings. We compared clinical outcomes of adults who started SGLT2i or… read more here.

Keywords: sglt2i; routine care; dpp4i; cardiovascular renal ... See more keywords

#412 Influence of SGLT2I on tubulointerstitium in DKD patients with moderate renal dysfunction

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.061

Abstract: In the FAGOTTO study (jRCTs041200069) to evaluate changes of renal hemodynamics on initial glomerular filtration rate (GFR) dip induced by Sodium-glucose cotransporter 2 inhibitors (SGLT2i) in patients (pts) with type 2 diabetic kidney disease (DKD)… read more here.

Keywords: moderate renal; gcr group; group; dkd ... See more keywords

#462 Initiation of SGLT2i vs GLP1-RA and incidence of AKI in persons with type 2 diabetes mellitus

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.111

Abstract: Adverse kidney outcomes, including acute kidney injury (AKI), are frequent complications in people with diabetes mellitus type 2. In large placebo-controlled randomized trials, both sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1-RA) have… read more here.

Keywords: diabetes mellitus; incidence aki; sglt2i glp1; glp1 ... See more keywords

#1392 MEST-C score correlation with proteinuria reduction after SGLT2i treatment in patients with IgA nephropathy

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.1331

Abstract: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are associated with better cardiovascular outcomes and with nephroprotection independent of diabetes status. Recent data suggest that SGLT2i significantly reduce proteinuria in patients with IgA nephropathy (IgAN). Data available for… read more here.

Keywords: treatment; mest score; score; reduction ... See more keywords