Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
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DOI: 10.1093/nar/gkx1268
Abstract: Abstract Genome editing with the CRISPR–Cas9 system has enabled unprecedented efficacy for reverse genetics and gene correction approaches. While off-target effects have been successfully tackled, the effort to eliminate variability in sgRNA efficacies—which affect experimental… read more here.
Keywords: crispr cas9; efficacy; sgrna efficacy; efficacy prediction ... See more keywords