The SH3-binding domain of Cx43 participates in loop/tail interactions critical for Cx43-hemichannel activity
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2722-7
Abstract: Connexin 43 (Cx43) hemichannels establish local signaling networks via the release of ATP and other molecules, but their excessive opening may result in cell death. Hence, the activity of Cx43-hemichannels ought to be critically controlled.… read more here.
Keywords: binding domain; hemichannel activity; sh3 binding; cx43 ... See more keywords