Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Sign Up to like & getrecommendations! Published in 2020 at "Structure"
DOI: 10.1016/j.str.2020.05.005
Abstract: STAC3 is a soluble protein essential for skeletal muscle excitation-contraction (EC) coupling. Through its tandem SH3 domains, it interacts with the cytosolic II-III loop of the skeletal muscle voltage-gated calcium channel. STAC3 is the target… read more here.
Keywords: contraction coupling; multiple sequence; sh3 domains; sequence variants ... See more keywords
Spatio-temporal regulation of endocytic protein assembly by SH3 domains in yeast
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1101/2022.08.11.503583
Abstract: Clathrin-mediated endocytosis is a conserved eukaryotic membrane trafficking pathway that is driven by a sequentially assembled molecular machinery that contains over 60 different proteins. SH3 domains are the most abundant protein-protein interaction domain in this… read more here.
Keywords: sh3; domain; sh3 domains; regulation endocytic ... See more keywords
Optimizing the Amino Acid Sequences of Peptides and Improving Their Specificity of Binding to SH3 Domains of Target Proteins
Sign Up to like & getrecommendations! Published in 2017 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.51.1.7
Abstract: Introduction: It is always a crucial challenge in biotechnology to avoid promiscuous binding between an anticancer peptide and multiple SH3 domains, thus reducing potential toxic effects. In spite of a great deal of experimental efforts,… read more here.
Keywords: peptide; amino acid; sh3 domains; acid sequence ... See more keywords