Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.
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DOI: 10.1016/j.jmb.2017.12.008
Abstract: The HIV-1 accessory protein Nef controls multiple aspects of the viral life cycle and host immune response, making it an attractive therapeutic target. Previous X-ray crystal structures of Nef in complex with key host cell… read more here.
Keywords: src family; family kinase; sh3 sh2; family ... See more keywords