Characterizing the fluid dynamics in the flow fields of cylindrical orbitally shaken bioreactors with different geometry sizes
Sign Up to like & getrecommendations! Published in 2018 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201700170
Abstract: Orbitally shaken bioreactors (OSRs) are commonly used for the cultivation of mammalian cells in suspension. To aid the geometry designing and optimizing of OSRs, we conducted a three‐dimensional computational fluid dynamics (CFD) simulation to characterize… read more here.
Keywords: fluid dynamics; flow fields; geometry; shaken bioreactors ... See more keywords
Analysis of volumetric mass transfer coefficient (kLa) in small- (250 mL) to large-scale (2500 L) orbitally shaken bioreactors
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02352-9
Abstract: In this study, the combination of dimensional analysis (DA) and analysis of variance (ANOVA) was used to predict the volumetric mass transfer coefficient (kLa) values under different operating conditions for orbitally shaken bioreactors (OSRs) with… read more here.
Keywords: coefficient kla; volumetric mass; mass transfer; transfer coefficient ... See more keywords