Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity.
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DOI: 10.1016/j.celrep.2020.02.088
Abstract: Epithelial cells establish apicobasal polarity by forming tight junctions (TJs) at the apical-lateral boundary, which play fundamental roles in physiological functions. An evolutionarily conserved atypical protein kinase C (aPKC)-partitioning defective (PAR) complex functions as a… read more here.
Keywords: cell polarity; polarity; rap1; shank2 binds ... See more keywords