Transcriptome analyses suggest minimal effects of Shank3 dosage on directional gene expression changes in the mouse striatum
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DOI: 10.1080/19768354.2019.1595142
Abstract: ABSTRACT Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for… read more here.
Keywords: dosage; expression changes; gene expression; shank3 dosage ... See more keywords