Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2022.4974
Abstract: Key Points Question To what extent are shared genetic determinants in the comorbidities and associations between gastrointestinal tract diseases and psychiatry disorders involved in the gut-brain axis? Findings In this genome-wide pleiotropic association study using… read more here.
Keywords: brain axis; shared genetic; etiology; gut brain ... See more keywords
Analysis of family histories suggests shared genetic risk for chronic thromboembolic pulmonary hypertension and venous thromboembolism
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12170
Abstract: Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) and acute pulmonary embolism (PE) are related phenotypes, however, previous reports have suggested that genetic risk factors for CTEPH and PE differ. Here we report that a family history… read more here.
Keywords: pulmonary hypertension; shared genetic; thromboembolic pulmonary; risk ... See more keywords
M61 Shared Genetic Variants Between Schizophrenia And General Cognitive Function Indicate Common Molecular Genetic Mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.452
Abstract: Background: Schizophrenia (SCZ) is a severe mental disorder characterized by widespread cognitive impairments including deficits in learning, memory, processing speed, attention and executive funct ... read more here.
Keywords: variants schizophrenia; m61 shared; schizophrenia general; genetic variants ... See more keywords
Shared genetic influences among childhood shyness, social competences, and cortical responses to emotions.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of experimental child psychology"
DOI: 10.1016/j.jecp.2017.03.012
Abstract: Visual event-related potentials (ERPs) evoked by facial expressions are useful to map socioemotional responses among shy children and to predict transition into social phobia. We investigated the sources of covariation among childhood shyness, social competences,… read more here.
Keywords: shared genetic; social competences; shyness social; among childhood ... See more keywords
Shared genetic effects of emotion and subcortical volumes in healthy adults
Sign Up to like & getrecommendations! Published in 2022 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2022.118894
Abstract: Ample studies have reported a strong association between emotion and subcortical volumes; still, the underlying mechanism regarding this relation remains unclear. Using a twin design, the current study aimed to explore the intrinsic association between… read more here.
Keywords: genetic effects; subcortical volumes; shared genetic; caudate volume ... See more keywords
Shared genetic risk factors for depression and stroke
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2019.03.003
Abstract: BACKGROUND The comorbidity of major depressive disorder (MDD) and stroke are common in clinic. There is a growing body of evidence suggesting a bi-directional relationship between stroke and depression. However, the mechanisms underlying the relationship… read more here.
Keywords: risk; risk factors; mdd stroke; shared genetic ... See more keywords
Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits
Sign Up to like & getrecommendations! Published in 2018 at "Psychological Medicine"
DOI: 10.1017/s0033291718001812
Abstract: Abstract Background Cardiovascular diseases represent a major health issue in patients with schizophrenia (SCZ) and bipolar disorder (BD), but the exact nature of cardiometabolic (CM) abnormalities involved and the underlying mechanisms remain unclear. Psychiatric medications… read more here.
Keywords: exploring shared; genetic bases; bipolar disorder; shared genetic ... See more keywords
Shared genetic aetiology between cognitive performance and brain activations in language and math tasks
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35665-0
Abstract: Cognitive performance is highly heritable. However, little is known about common genetic influences on cognitive ability and brain activation when engaged in a cognitive task. The Human Connectome Project (HCP) offers a unique opportunity to… read more here.
Keywords: etiology; cognitive performance; language; performance ... See more keywords
The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology.
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral cortex"
DOI: 10.1093/cercor/bhy216
Abstract: Individual differences in educational attainment are linked to differences in intelligence, and predict important social, economic, and health outcomes. Previous studies have found common genetic factors that influence educational achievement, cognitive performance and total brain… read more here.
Keywords: educational attainment; genetic basis; cortical morphology; shared genetic ... See more keywords
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci.
Sign Up to like & getrecommendations! Published in 2023 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbad063
Abstract: Low vitamin D (vitD) levels have been consistently reported in schizophrenia (SCZ) suggesting a role in the etiopathology. However, little is known about the role of underlying shared genetic mechanisms. We applied a conditional/conjunctional false… read more here.
Keywords: shared genetic; genome wide; wide association; scz ... See more keywords
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets
Sign Up to like & getrecommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13372
Abstract: The genetic relationship between schizophrenia (SCZ) and other nonpsychiatric disorders remains largely unknown. We examined the shared genetic components between these disorders based on multipopulation data sets. read more here.
Keywords: shared genetic; components metabolic; genetic components; data sets ... See more keywords