RippleNet: a Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection
Sign Up to like & getrecommendations! Published in 2021 at "Neuroinformatics"
DOI: 10.1007/s12021-020-09496-2
Abstract: Hippocampal sharp wave ripples (SPW-R) have been identified as key bio-markers of important brain functions such as memory consolidation and decision making. Understanding their underlying mechanisms in healthy and pathological brain function and behaviour rely… read more here.
Keywords: detection; sharp wave; spw detection; recurrent neural ... See more keywords
Origin of Gamma Frequency Power during Hippocampal Sharp-Wave Ripples
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.10.066
Abstract: SUMMARY Hippocampal sharp-wave ripples (SPW-Rs) support consolidation of recently acquired episodic memories and planning future actions by generating ordered neuronal sequences of previous or future experiences. SPW-Rs are characterized by several spectral components: a slow… read more here.
Keywords: frequency; sharp wave; power; hippocampal sharp ... See more keywords
A large majority of awake hippocampal sharp-wave ripples feature spatial trajectories with momentum
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2021.11.014
Abstract: During periods of rest, hippocampal place cells feature bursts of activity called sharp-wave ripples (SWRs). Heuristic approaches have revealed that a small fraction of SWRs appear to "simulate" trajectories through the environment, called awake hippocampal… read more here.
Keywords: awake hippocampal; sharp wave; trajectories momentum; wave ripples ... See more keywords
The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Neuroscience"
DOI: 10.1038/s41583-018-0077-1
Abstract: Various cognitive functions have long been known to require the hippocampus. Recently, progress has been made in identifying the hippocampal neural activity patterns that implement these functions. One such pattern is the sharp wave–ripple (SWR),… read more here.
Keywords: wave ripple; memory retrieval; consolidation; sharp wave ... See more keywords
A Novel Biophysical Model for the Generation of Sharp Wave Ripples in CA1 Hippocampus
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Circuits and Systems II: Express Briefs"
DOI: 10.1109/tcsii.2023.3262207
Abstract: Synchronous activities among neurons in the brain generate emergent network oscillations such as the hippocampal Sharp-wave ripples (SPWRs) that facilitate information processing during memory formation. However, how neurons and circuits are functionally organized to generate… read more here.
Keywords: network; ca1 hippocampus; wave ripples; model ... See more keywords
Long-duration hippocampal sharp wave ripples improve memory
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aax0758
Abstract: Longer ripples make better memories Sharp wave ripples in the hippocampus are thought to play a role in memory formation and action planning. Fernández-Ruiz et al. used multisite electrophysiological recordings combined with optogenetic activation of… read more here.
Keywords: long duration; sharp wave; duration; hippocampal ... See more keywords
Probing subthreshold dynamics of hippocampal neurons by pulsed optogenetics
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abm1891
Abstract: Understanding how excitatory (E) and inhibitory (I) inputs are integrated by neurons requires monitoring their subthreshold behavior. We probed the subthreshold dynamics using optogenetic depolarizing pulses in hippocampal neuronal assemblies in freely moving mice. Excitability… read more here.
Keywords: place cells; sharp wave; place fields; excitability ... See more keywords
Alterations in theta-gamma coupling and sharp wave-ripple, signs of prodromal hippocampal network impairment in the TgF344-AD rat model
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1081058
Abstract: Alzheimer’s disease (AD) is a severe neurodegenerative disorder caused by the accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to dementia. Disease-modifying therapies are still lacking, due to incomplete insights into the… read more here.
Keywords: wave ripple; network; tgf344; theta gamma ... See more keywords
Deep learning-based feature extraction for prediction and interpretation of sharp-wave ripples in the rodent hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77772
Abstract: Local field potential (LFP) deflections and oscillations define hippocampal sharp-wave ripples (SWRs), one of the most synchronous events of the brain. SWRs reflect firing and synaptic current sequences emerging from cognitively relevant neuronal ensembles. While… read more here.
Keywords: wave ripples; rodent hippocampus; learning based; deep learning ... See more keywords