Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Epidemiology"
DOI: 10.1007/s10654-024-01136-2
Abstract: Research has indicated that sex hormone-binding globulin (SHBG) is associated with glucose homeostasis and may play a role in the etiology of type 2 diabetes (T2D). While it is unclear whether SHBG may mediate sex… read more here.
Keywords: differences glucose; sex differences; sex hormone; sex ... See more keywords
Aqueous solution interactions with sex hormone-binding globulin and estradiol: a theoretical investigation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9505-8
Abstract: Sex hormone-binding globulin (SHBG) is a binding protein that regulates the availability of steroid hormones in the plasma. Although best known as a steroid carrier, recent studies have associated SHBG in modulating behavioral aspects related… read more here.
Keywords: hormone; energy; shbg; sex hormone ... See more keywords
Evaluation of the Efficacy of Sex Hormone–Binding Globulin in Insulin Resistance Assessment Based on HOMA-IR in Patients with PCOS
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00535-0
Abstract: This study aimed to evaluate the efficacy of SHBG in predicting insulin resistance (IR) in newly diagnosed, untreated patients with polycystic ovary syndrome (PCOS). Hundred newly diagnosed, untreated patients with PCOS and 61 subjects without… read more here.
Keywords: overweight obese; shbg; group; pcos patients ... See more keywords
Mediated relationships between multiple metals exposure and fasting blood glucose by reproductive hormones in Chinese men.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.116791
Abstract: Previous studies have reported metals exposure contribute to the change of fasting blood glucose (FBG) level. However, the roles of reproductive hormones in their associations have not been fully elucidated. The aim of the study… read more here.
Keywords: fasting blood; shbg; reproductive hormones; blood glucose ... See more keywords
Causal effect of sex hormone-binding globulin and testosterone on coronary heart disease: A multivariable and network Mendelian randomization analysis.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2021.06.037
Abstract: BACKGROUND Although observational studies have shown an association between sex hormone-binding globulin (SHBG), testosterone (T) and cardiovascular diseases (CVD), controversy remains. In this study, we aim to explore the causal effects of SHBG and T… read more here.
Keywords: causal effect; shbg; analysis; chd ... See more keywords
Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states
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DOI: 10.1016/j.isci.2021.102414
Abstract: Summary Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer with… read more here.
Keywords: hormone; shbg; estradiol binding; sex hormone ... See more keywords
Tree nut consumption is associated with higher sex hormone-binding globulin levels in premenopausal US women.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition research"
DOI: 10.1016/j.nutres.2021.07.003
Abstract: Low levels of sex hormone-binding globulin (SHBG) are associated with many diseases including hypertension, diabetes, and polycystic ovarian syndrome. Walnuts increased circulating SHBG in 31 women complicated with polycystic ovarian syndrome. However, whether tree nuts… read more here.
Keywords: premenopausal women; tree nuts; shbg; nut consumption ... See more keywords
Association between human SHBG gene polymorphisms and risk of PCOS: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2020.10.003
Abstract: Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds androgens and oestrogens, and regulates their bioavailability to target tissues. To date, several human SHBG gene polymorphisms have been identified. Polycystic ovary syndrome (PCOS) is… read more here.
Keywords: risk pcos; gene polymorphisms; shbg; shbg gene ... See more keywords
Lower SHBG level is associated with higher leptin and lower adiponectin levels as well as metabolic syndrome, independent of testosterone
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03078-0
Abstract: In addition to testosterone (T), the emerging role of sex hormone-binding globulin (SHBG) in pathogenesis of metabolic syndrome (MetS) has been noted recently. However, reports of associations with serum adipocytokine levels are still limited. Therefore,… read more here.
Keywords: shbg; leptin levels; testosterone; adiponectin ... See more keywords
Nonlinear association of sex hormone-binding globulin levels and chronic kidney disease, an analysis based on the National Health and Nutrition Examination Survey (NHANES) 2013–2016
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DOI: 10.1080/0886022x.2024.2409341
Abstract: Abstract Studies on the relationship between serum sex hormone-binding globulin (SHBG) levels and chronic kidney disease (CKD) remain limited and inconclusive. Therefore, this study aims to evaluate the effects of SHBG on CKD in a… read more here.
Keywords: ckd; sex hormone; hormone binding; shbg levels ... See more keywords
Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats
Sign Up to like & getrecommendations! Published in 2022 at "Physiological and Biochemical Zoology"
DOI: 10.1086/721154
Abstract: Brown bears are obese when they enter the den, and after 6 mo of hibernation and physical inactivity, bears show none of the adverse consequences of a sedentary lifestyle in humans, such as cardiovascular disease,… read more here.
Keywords: shbg; hormones hibernating; brown bears; steroid hormones ... See more keywords