ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.70022
Abstract: Triple‐negative breast cancer (TNBC) is highly metastatic and presents clinical challenges given the lack of targeted therapies. Here, we report that the ShcD phosphotyrosine adaptor protein is upregulated in TNBC, and its expression correlates with… read more here.
Keywords: breast cancer; breast; shcd; triple negative ... See more keywords
The role of the ShcD and RET interaction in neuroblastoma survival and migration
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2018.01.007
Abstract: Preliminary screening data showed that the ShcD adaptor protein associates with the proto-oncogene RET receptor tyrosine kinase. In the present study, we aimed to investigate the molecular interaction between ShcD and RET in human neuroblastoma… read more here.
Keywords: role shcd; shcd; shcd ret; neuroblastoma ... See more keywords