Sex-Specific Response to Combinations of Shear Stress and Substrate Stiffness by Endothelial Cells In Vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100735
Abstract: By using a full factorial design of experiment, the combinatorial effects of biological sex, shear stress, and substrate stiffness on human umbilical vein endothelial cell (HUVEC) spreading and Yes-associated protein 1 (YAP1) activity are able… read more here.
Keywords: stress substrate; sex; shear stress; substrate stiffness ... See more keywords
Shear stress computation in a millimeter thin flat panel photobioreactor: Numerical design validated by experiments
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1894
Abstract: Flat panels are the most spread type of photobioreactors for studying light effects on a microalgae culture. Their low thickness, usually between 1 and 3 cm, aims at ensuring light homogeneity across the culture. Yet… read more here.
Keywords: thin flat; flat panel; photobioreactor; shear stress ... See more keywords
Control of gene expression in engineered mammalian cells with a programmable shear-stress inducer.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.27939
Abstract: In humans, cellular mechanoperception serves as the basis of touch sensation and proprioception, contributes to the proper programming of cell fate during embryonic development, and plays a pivotal role in the development of mechanosensitive tissues.… read more here.
Keywords: control gene; gene; shear stress; gene expression ... See more keywords
Mechano‐regulation of Wnt/β‐Catenin signaling to control paraxial versus lateral mesoderm lineage bifurcation
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Progress"
DOI: 10.1002/btpr.3312
Abstract: Mechanical cues are involved in many biological processes, including embryonic development and patterning. For example, external mechanical forces (shear stress), lateral cell–cell interactions, and mechanical properties (stiffness and composition) of the extracellular matrix are thought… read more here.
Keywords: stress; wnt catenin; catenin signaling; differentiation ... See more keywords
Keratinocytes are mechanoresponsive to the microflow‐induced shear stress
Sign Up to like & getrecommendations! Published in 2019 at "Cytoskeleton"
DOI: 10.1002/cm.21521
Abstract: Here, we have reported that keratinocytes respond to the microflow‐induced shear stress both at the collective and individual cell level. Using a microfluidic setup, we categorically showed that low shear stress of magnitude 0.06 dyne/cm2… read more here.
Keywords: induced shear; microflow induced; shear stress; stress ... See more keywords
Ventricular wall stress and wall shear stress homeostasis predicts cardiac remodeling during pregnancy: A modelling study.
Sign Up to like & getrecommendations! Published in 2021 at "International journal for numerical methods in biomedical engineering"
DOI: 10.1002/cnm.3536
Abstract: Pregnancy is a unique and dynamic process characterized by significant changes in the maternal cardiovascular system that are required to satisfy the increased maternal and fetal metabolic demands. Profound structural and hemodynamic adaptations occur during… read more here.
Keywords: pregnancy; wall shear; shear stress; stress ... See more keywords
Hemodynamic investigation of a novel rotary displacement blood pump for extracorporeal membrane oxygenation.
Sign Up to like & getrecommendations! Published in 2023 at "International journal for numerical methods in biomedical engineering"
DOI: 10.1002/cnm.3705
Abstract: Extracorporeal membrane oxygenation (ECMO) is a life support system used in the treatment of severe respiratory and circulatory failure. High shear stress caused by the high rotational speed of centrifugal blood pumps can cause hemolysis… read more here.
Keywords: shear stress; blood pump; rdbp; pump ... See more keywords
A modified Raupach's model applicable for shear‐stress partitioning on surfaces covered with dense and flat‐shaped gravel roughness elements
Sign Up to like & getrecommendations! Published in 2021 at "Earth Surface Processes and Landforms"
DOI: 10.1002/esp.5052
Abstract: A commonly used measure to prevent soil wind erosion is to cover the surface with gravel. Gravel can inhibit soil erosion by covering the surface directly, changing the airflow field near the surface and sharing… read more here.
Keywords: shear stress; roughness elements; stress; flat shaped ... See more keywords
The protective effects of azilsartan against oscillatory shear stress‐induced endothelial dysfunction and inflammation are mediated by KLF6
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22766
Abstract: Atherosclerosis is a common cardiovascular disease with high morbidity and mortality. It is reported to be related to oscillatory shear stress (OSS)‐induced endothelial dysfunction and excessive production of inflammatory factors. Azilsartan, a specific antagonist of… read more here.
Keywords: induced endothelial; shear stress; effects azilsartan; oscillatory shear ... See more keywords
c‐Abl tyrosine kinase regulates neutrophil crawling behavior under fluid shear stress via Rac/PAK/LIMK/cofilin signaling axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26453
Abstract: The excessive recruitment and improper activation of polymorphonuclear neutrophils (PMNs) often induces serious injury of host tissues, leading to inflammatory disorders. Therefore, to understand the molecular mechanism on neutrophil recruitment possesses essential pathological and physiological… read more here.
Keywords: abl kinase; kinase; shear stress; cofilin signaling ... See more keywords
Laminar shear stress promotes mitochondrial homeostasis in endothelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26375
Abstract: Vascular endothelial cells (ECs) are constantly subjected to flow‐induced shear stress that is crucial for endothelial functions. Laminar shear stress (LSS) exerts atheroprotection to ECs. Mitochondrial homeostasis is essential for cellular survival. However, the effects… read more here.
Keywords: homeostasis; shear stress; ecs; mitochondrial homeostasis ... See more keywords