Can the sheep model fully represent the human model for the functional evaluation of cervical interbody fusion cages?
Sign Up to like & getrecommendations! Published in 2019 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-018-1104-x
Abstract: AbstractSheep model is the most favourable choice for animal study for functional evaluation of the cervical fusion prostheses before clinical application; however, significantly large differences between sheep and human existed in terms of morphological characteristics… read more here.
Keywords: functional evaluation; sheep model; model; evaluation cervical ... See more keywords
Assessment of the immunogenicity of the leptospiral LipL32, LigAni, and LigBrep recombinant proteins in the sheep model.
Sign Up to like & getrecommendations! Published in 2019 at "Comparative immunology, microbiology and infectious diseases"
DOI: 10.1016/j.cimid.2019.05.012
Abstract: Veterinary leptospirosis vaccines are composed of bacterins and present limitations, for example, the need for bacteriological culture and serovar-dependent immunity. Recombinant antigens represent a promising alternative. LigAni, LigBrep, and LipL32 proteins have been shown to… read more here.
Keywords: lipl32; recombinant proteins; ligani ligbrep; group ... See more keywords
Multimodal preoperative imaging for transcatheter mitral valve replacement in the domestic sheep model
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-62646-3
Abstract: Preclinical in vivo evaluation is an essential step in the progression of new cardiac devices into patient use, with studies predominantly performed in the domestic sheep model. A growing area of interest in cardiac device… read more here.
Keywords: mitral valve; domestic sheep; transcatheter mitral; sheep model ... See more keywords
P-788 Analysis of tissue regeneration after transplantation of bioengineered uterine grafts in a sheep model of uterine injury
Sign Up to like & getrecommendations! Published in 2024 at "Human Reproduction"
DOI: 10.1093/humrep/deae108.1102
Abstract: Can we regenerate a damaged uterus using decellularized (further repopulated with stem cells or not) uterine scaffolds in a sheep model? Bioengineered uterine grafts can promote the regeneration of a damaged uterus, but this process… read more here.
Keywords: uterine grafts; analysis; sheep model; regeneration ... See more keywords
Associations between fetal heart rate variability and umbilical cord occlusions‐induced neural injury: An experimental study in a fetal sheep model
Sign Up to like & getrecommendations! Published in 2022 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.14352
Abstract: This study evaluated the association between fetal heart rate variability (HRV) and the occurrence of hypoxic–ischemic encephalopathy in a fetal sheep model. read more here.
Keywords: fetal heart; sheep model; rate variability; fetal sheep ... See more keywords
Abstract 113: Real-Time Detection of Cerebral Ischemia Using Optical Brain Pulse Monitoring in a Sheep Model of Stroke
Sign Up to like & getrecommendations! Published in 2025 at "Stroke"
DOI: 10.1161/str.56.suppl_1.113
Abstract: Background: Early detection and intervention of cerebral ischemia is critical to improving patient outcomes. Optical brain pulse monitoring (OBPM) is a unique technique that offers non-invasive, continuous monitoring of brain hemodynamics via brain pulse waveform… read more here.
Keywords: brain pulse; brain; time; sheep model ... See more keywords
Abstract WP367: Attenuating Post-stroke Ischemia Reperfusion Injury: Establishing the Efficacy of Disodium Malonate in a Clinically Relevant Sheep Model
Sign Up to like & getrecommendations! Published in 2025 at "Stroke"
DOI: 10.1161/str.56.suppl_1.wp367
Abstract: Introduction: Ischemia reperfusion injury (IRI) is a paradoxical and deleterious consequence of current interventions for acute ischemic stroke (AIS). Rapid restoration of oxygen to brain tissue upon reperfusion initiates mitochondrial reverse electron transport (RET) and… read more here.
Keywords: ischemia reperfusion; reperfusion; reperfusion injury; post ... See more keywords
Sheep model of haemodialysis treatment
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DOI: 10.1177/0023677217718861
Abstract: More than two million patients received haemodialysis (HD) in 2013. Many methods for improving dialysis therapy outcomes have been tested. Nevertheless, patients continue to experience high morbidity and mortality rates. We aimed to develop an… read more here.
Keywords: sheep model; treatment; model haemodialysis; physiology ... See more keywords
Absorbance or organization into ankylosis: a microarray analysis of haemarthrosis in a sheep model of temporomandibular joint trauma
Sign Up to like & getrecommendations! Published in 2021 at "BMC Oral Health"
DOI: 10.1186/s12903-021-02033-w
Abstract: Background Traumatic haemarthrosis was hypothesized to be the etiology of temporomandibular (TMJ) ankylosis. Here, taking haematoma absorbance as a control, we aimed to reveal the molecular mechanisms involved in haematoma organizing into ankylosis using transcriptome… read more here.
Keywords: sheep model; absorbance; microarray; haemarthrosis ... See more keywords
Prenatal testosterone excess disrupts placental function in a sheep model of polycystic ovary syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "Endocrinology"
DOI: 10.1210/en.2019-00386
Abstract: Polycystic ovary syndrome (PCOS) is a common condition of reproductive aged women. In a well-validated sheep model of PCOS, testosterone (T) treatment of pregnant ewes culminated in placental insufficiency and intrauterine growth restriction of offspring.… read more here.
Keywords: ovary syndrome; polycystic ovary; placental function; sheep model ... See more keywords
Developmental programming of the neuroendocrine axis by steroid hormones: Insights from the sheep model of PCOS
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1096187
Abstract: The reproductive neuroendocrine system is a key target for the developmental programming effects of steroid hormones during early life. While gonadal steroids play an important role in controlling the physiological development of the neuroendocrine axis,… read more here.
Keywords: steroid hormones; sheep model; neuroendocrine axis; developmental programming ... See more keywords