Tautomeric Effect of Histidine on β-Sheet Formation of Amyloid Beta 1-40: 2D-IR Simulations.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2020.07.009
Abstract: Histidine state (protonated or δ or ε tautomer) has been considered the origin of abnormal misfolding and aggregation of β-amyloid (Aβ). Our previous studies reported that the δδδ isomer of Aβ (1-40) has a greater… read more here.
Keywords: histidine; tautomeric effect; sheet formation;
Conformation and dynamics of soluble repetitive domain elucidates the initial β-sheet formation of spider silk
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DOI: 10.1038/s41467-018-04570-5
Abstract: The β-sheet is the key structure underlying the excellent mechanical properties of spider silk. However, the comprehensive mechanism underlying β-sheet formation from soluble silk proteins during the transition into insoluble stable fibers has not been… read more here.
Keywords: repetitive domain; sheet formation; sheet; silk ... See more keywords