Pseudo-allergic compounds screened from Shengmai Injection by using high-expression Mas-related G protein-coupled receptor X2 cell membrane chromatography online coupled with liquid chromatography and mass spectrometry.
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DOI: 10.1002/jssc.202001163
Abstract: Adverse drug reactions of Traditional Chinese medicine injection mainly manifested as pseudo-allergic reactions. In the present study, ginsenoside Rd, Ro and Rg3 were identified as pseudo-allergic components in Shengmai Injection by a high-expression Mas-related G… read more here.
Keywords: chromatography; mas related; shengmai injection; pseudo allergic ... See more keywords
In vivo and in vitro protective effects of shengmai injection against doxorubicin-induced cardiotoxicity
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DOI: 10.1080/13880209.2022.2046801
Abstract: Abstract Context Shengmai injection (SMI) has been used to treat heart failure. Objective This study determines the molecular mechanisms of SMI against cardiotoxicity caused by doxorubicin (DOX). Materials and methods In vivo, DOX (15 mg/kg) was… read more here.
Keywords: shengmai injection; smi fold; cardiotoxicity; smi ... See more keywords
Efficacy and safety of Shengmai injection as an adjunctive therapy on sepsis
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DOI: 10.1097/md.0000000000028493
Abstract: Abstract Introduction: Sepsis is a common life-threatening, acute and severe disease with high morbidity and mortality, which seriously endangers patient health. Shengmai injection (SMI) is typically used as an alternative treatment for sepsis patients. This… read more here.
Keywords: sepsis; shengmai injection; therapy sepsis; safety ... See more keywords