Full-length dhh and N-terminal shh act as competitive antagonists to regulate angiogenesis and vascular permeability.
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DOI: 10.1093/cvr/cvaa285
Abstract: The therapeutic potential of Hedgehog (Hh) signalling agonists for vascular diseases is of growing interest. However, molecular and cellular mechanisms underlying the role of the Hh signalling in vascular biology remain poorly understood. AIMS The… read more here.
Keywords: dhh; shh; full length; shh act ... See more keywords