Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups.
Sign Up to like & getrecommendations! Published in 2023 at "Neuro-oncology"
DOI: 10.1093/neuonc/noad027
Abstract: BACKGROUND The prognostic impact of clinical risk factors and DNA methylation patterns in sonic hedgehog (SHH)-activated early childhood desmoplastic/nodular medulloblastoma (DMB) or medulloblastoma with extensive nodularity (MBEN) were evaluated to better identify patients at risk… read more here.
Keywords: shh; early childhood; medulloblastoma; shh shh ... See more keywords
Pediatric Patients With SHH Medulloblastoma Fail Differently as Compared With Adults: Possible Implications for Treatment Modifications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001484
Abstract: Purpose: The purpose of this work was to study the diversity of sonic hedgehog (SHH) medulloblastoma across different age groups with an emphasis on patterns of relapse. Methods: All data for the study were obtained… read more here.
Keywords: shh medulloblastoma; shh shh; treatment; histology ... See more keywords