LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "shh signaling" as a keyword



Photo from wikipedia

Inhibition of MicroRNA-195 Alleviates Neuropathic Pain by Targeting Patched1 and Inhibiting SHH Signaling Pathway Activation

Sign Up to like & get
recommendations! Published in 2019 at "Neurochemical Research"

DOI: 10.1007/s11064-019-02797-2

Abstract: Trigeminal neuralgia (TN) is a type of chronic neuropathic pain that is caused by peripheral nerve lesions that result from various conditions, including the compression of vessels, tumors and viral infections. MicroRNAs (miRs) are increasingly… read more here.

Keywords: mir 195; patched1; signaling pathway; neuropathic pain ... See more keywords
Photo by nixcreative from unsplash

ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells

Sign Up to like & get
recommendations! Published in 2021 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2020.111055

Abstract: The myoblast is a precursor cell that rebuilds muscle tissue after trauma in human and animal skeletal muscle tissue. Proliferation of myoblasts is important for skeletal muscle damage repair and is controlled by numerous transcription… read more here.

Keywords: skeletal muscle; shh signaling; c2c12; proliferation ... See more keywords

Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.

Sign Up to like & get
recommendations! Published in 2017 at "Developmental biology"

DOI: 10.1016/j.ydbio.2017.04.002

Abstract: Sonic Hedgehog (Shh) signaling regulates the patterning of ventral spinal cord through the effector Gli family of transcription factors. Previous in vitro studies showed that an E3 ubiquitin ligase containing Speckle-type POZ protein (Spop) targets… read more here.

Keywords: cord; shh signaling; spop; cord patterning ... See more keywords
Photo by tcwillmott from unsplash

Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment

Sign Up to like & get
recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-02063-x

Abstract: Deregulated Sonic Hedgehog (SHH) pathway facilitates the initiation, progression, and metastasis of Non-small cell lung cancer (NSCLC), confers drug resistance and renders a therapeutic interference option to lung cancer patients with poor prognosis. In this… read more here.

Keywords: shh signaling; progression; signaling pathway; lung cancer ... See more keywords
Photo from archive.org

Zebrafish spinal cord oligodendrocyte formation requires boc function.

Sign Up to like & get
recommendations! Published in 2021 at "Genetics"

DOI: 10.1093/genetics/iyab082

Abstract: The axis of the vertebrate neural tube is patterned, in part, by a ventral to dorsal gradient of Shh signaling. In the ventral spinal cord, Shh induces concentration-dependent expression of transcription factors, subdividing neural progenitors… read more here.

Keywords: shh signaling; cord; boc function; spinal cord ... See more keywords

Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression

Sign Up to like & get
recommendations! Published in 2022 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjab082

Abstract: ABSTRACT Sonic hedgehog (Shh) signaling is essential for the proliferation of cerebellar granule neuron progenitors (CGNPs), and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma (MB). During vertebrate neural development, RNF220, a… read more here.

Keywords: rnf220; shh; development; shh signaling ... See more keywords
Photo by nci from unsplash

Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells in Vitro via Regulation of Sirt1

Sign Up to like & get
recommendations! Published in 2018 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000494593

Abstract: Background/Aims: Injuries of the brain and spinal cord result in the formation of glial (reactive gliosis) and fibrotic (formed by fibroblasts) scars. Recent studies have shown that the fibrotic scar was much more important for… read more here.

Keywords: resveratrol; nih3t3 cells; viability nih3t3; shh signaling ... See more keywords
Photo from wikipedia

Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

Sign Up to like & get
recommendations! Published in 2018 at "Biology Open"

DOI: 10.1242/bio.035592

Abstract: ABSTRACT In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs… read more here.

Keywords: intervertebral discs; sonic hedgehog; shh signaling; discs ... See more keywords
Photo from wikipedia

Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components

Sign Up to like & get
recommendations! Published in 2022 at "Journal of Cell Science"

DOI: 10.1242/jcs.259209

Abstract: ABSTRACT Cilia are evolutionarily conserved organelles that orchestrate a variety of signal transduction pathways, such as sonic hedgehog (SHH) signaling, during embryonic development. Our recent studies have shown that loss of GID ubiquitin ligase function… read more here.

Keywords: ubiquitin ligase; protein homeostasis; sonic hedgehog; shh signaling ... See more keywords