A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.01.008
Abstract: Figure 3. Tumor Immunity in the Microenvironment Classification Four different TME groups with potential implications for mechanism and therapy have been identified according to B7-H1 (PD-L1) expression and the presence of TILs in tumor biopsies:… read more here.
Keywords: tils considered; paradigm shift; shift cancer; expression ... See more keywords
In a major shift, cancer drugs go 'tissue-agnostic'.
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.356.6343.1111
Abstract: Since the beginnings of cancer chemotherapy in the 1940s, oncologists have treated patients with drugs based on the organ or tissue where their tumors originated. Colon cancer requires different drug regimens than lung, breast, or… read more here.
Keywords: cancer drugs; shift cancer; drug; major shift ... See more keywords