Structure Determination of Challenging Protein-Peptide Complexes Combining NMR Chemical Shift Data and Molecular Dynamics Simulations
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c01595
Abstract: Intrinsically disordered regions of proteins often mediate important protein-protein interactions. However, the folding-upon-binding nature of many polypeptide-protein interactions limits the ability of modeling tools to predict the three-dimensional structures of such complexes. To address this… read more here.
Keywords: shift data; chemical shift; combining nmr; peptide ... See more keywords
MedShift: Automated Identification of Shift Data for Medical Image Dataset Curation.
Sign Up to like & getrecommendations! Published in 2023 at "IEEE journal of biomedical and health informatics"
DOI: 10.1109/jbhi.2023.3275104
Abstract: Automated curation of noisy external data in the medical domain has long been in high demand, as AI technologies need to be validated using various sources with clean, annotated data. Identifying the variance between internal… read more here.
Keywords: shift data; curation; internal external; shift ... See more keywords