1,5-Hydride-Shift-Triggered Cyclization for the Synthesis of Unsymmetric Julolidines
Sign Up to like & getrecommendations! Published in 2021 at "Synthesis"
DOI: 10.1055/a-1559-2728
Abstract: Directly accessible 8-substituted tetrahydroquinolines undergo 1,5-hydride-shift-triggered cyclization to provide difficult to access julolidine derivatives in yields of 21–98% under scandium(III) triflate catalysis. Additionally, the scope of the reaction, several follow-up transformations and a remarkable side… read more here.
Keywords: shift triggered; hydride shift; triggered cyclization; synthesis unsymmetric ... See more keywords
Study on 1,4-hydride shift triggered spirocyclization of arylidene imidazolones: substituent control on formation of indane or tetrahydrobenzazepine systems
Sign Up to like & getrecommendations! Published in 2025 at "Mendeleev Communications"
DOI: 10.71267/mencom.7550
Abstract: A rare process of 1,4-hydride or formal 1,6-hydride shift occurs in the (o-dialkylaminomethyl)arylidene imidazolones under the action of aluminum chloride. Only sterically hindered amino derivatives are able to enter the spirocyclization reaction, and the substituent… read more here.
Keywords: arylidene imidazolones; hydride shift; indane; study hydride ... See more keywords