Crystal structure and functional characterization of SF216 from Shigella flexneri
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12873
Abstract: Shigella flexneri is a Gram‐negative anaerobic bacterium that causes highly infectious bacterial dysentery in humans. Here, we solved the crystal structure of SF216, a hypothetical protein from the S. flexneri 5a strain M90T, at 1.7… read more here.
Keywords: crystal structure; structure functional; structure; shigella flexneri ... See more keywords
Quantitative analysis of Shigella flexneri protein expression under acid stress
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DOI: 10.1002/pmic.201600381
Abstract: As an important foodborne pathogen, Shigella flexneri can cause widespread enteric infection with bacteria as few as hundreds. This is, at least in part, attributed to its robust anti‐acid strategies because passage through the highly… read more here.
Keywords: protein expression; shigella; shigella flexneri; acid ... See more keywords
Analysis of the Localization of NLRs upon Shigella flexneri Infection Exemplified by NOD1.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1944-5_3
Abstract: NOD-like receptors (NLRs) are a family of pattern recognition receptors, able to respond to conserved microbial structures and endogenous danger signals. The NLR NOD1 responds to bacterial peptidoglycan, leading to recruitment of RIPK2, following activation… read more here.
Keywords: localization nlrs; shigella flexneri; infection; nlrs upon ... See more keywords
Antimicrobial and anti-biofilm activity of thymoquinone against Shigella flexneri.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11295-x
Abstract: Shigella flexneri (Sh. flexneri), a common foodborne pathogen, has become one of the main threats to food safety and human health due to its high pathogenicity and persistent infection. The objective of this study was… read more here.
Keywords: antimicrobial anti; anti biofilm; flexneri; biofilm ... See more keywords
To Study the Anti-cancer Effects of Shigella Flexneri in AspC-1 Pancreatic Cancer Cell Line in Approach to Bax and bcl-2 Genes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-020-00433-9
Abstract: Cancer is the uncontrolled division of cells and can be caused by genetic or environmental factors. Pancreatic cancer is one of the deadliest among all cancers. The role of bacteria as an anticancer agent dates… read more here.
Keywords: bax bcl; pancreatic cancer; bcl genes; cancer ... See more keywords
Effects of Shigella flexneri exposure on development of Xenopus Tropicals embryo and its immune response.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.128153
Abstract: Shigella sp. is a highly infectious intestinal pathogen worthy of serious attention that is widely present in aquaculture water and some other polluted water types and might inhibit embryonic development as a biological pollutant. In… read more here.
Keywords: development; rate; embryonic development; shigella flexneri ... See more keywords
Monitoring Longitudinal Trends and Assessment of the Health Risk of Shigella flexneri Antimicrobial Resistance.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c08766
Abstract: Shigella flexneri infection is the main cause of diarrhea in humans worldwide. The emergence of antimicrobial resistance (AMR) of S. flexneri is a growing public health threat worldwide, while large-scale studies monitoring the longitudinal AMR… read more here.
Keywords: shigella flexneri; health; monitoring longitudinal; risk ... See more keywords
P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00465
Abstract: The discovery of clustered, regularly interspaced, short palindromic repeats (CRISPR) and the Cas9 RNA-guided nuclease provides unprecedented opportunities to selectively kill specific populations or species of bacteria. However, the use of CRISPR-Cas9 to clear bacterial… read more here.
Keywords: crispr cas9; shigella flexneri; delivery crispr; delivery ... See more keywords
Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116776119
Abstract: Significance Shigella flexneri, a deleterious bacterium, causes massive human infection cases and deaths worldwide. To facilitate survival and replication in infected host cells, S. flexneri can secrete two highly similar E3 ligase effectors, IpaH1.4 and… read more here.
Keywords: chain assembly; shigella flexneri; ubiquitin chain; assembly complex ... See more keywords
Asiatic Acid inhibits intracellular Shigella flexneri growth by inducing antimicrobial peptide gene expression.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied microbiology"
DOI: 10.1093/jambio/lxac076
Abstract: AIMS A rapid rise in resistance to conventional antibiotics for Shigella spp. has created a problem in treating shigellosis. Hence, there is an urgent need for new and non-conventional anti-bacterial agents. The aim of this… read more here.
Keywords: shigella flexneri; growth; antimicrobial peptide; acid ... See more keywords
Virulence plasmid pINV as a genetic signature for Shigella flexneri phylogeny
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000846
Abstract: Shigella flexneri is a major health burden in low- and middle-income countries, where it is a leading cause of mortality associated with diarrhoea in children, and shows an increasing incidence among travellers and men having… read more here.
Keywords: shigella flexneri; pinv; plasmid; virulence ... See more keywords