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   Articles with "shionogi" as a keyword



667. Real-world Experience of Cefiderocol with Pseudomonas aeruginosa in the PROVE (Retrospective Cefiderocol Chart Review) Study

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recommendations! Published in 2022 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofac492.719

Abstract: Gram-negative (GN) bacterial resistance is an urgent global health problem. Cefiderocol (CFDC) is active against many resistant GN pathogens, including Pseudomonas aeruginosa (PA). PROVE is an ongoing international, retrospective study assessment of CFDC use for… read more here.

Keywords: aeruginosa prove; pseudomonas aeruginosa; cfdc; shionogi ... See more keywords

P-1086. COT-832, a Novel Polyene Macrolide Antifungal (I): In Vitro Antifungal Activity against Candida, Aspergillus, and Mucor, etc., Hemolytic Activity, and Cytotoxicity

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recommendations! Published in 2025 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae631.1274

Abstract: Abstract Background A novel polyene macrolide antifungal, COT-832 was created by SHIONOGI through structurally modifying Amphotericin B(AmB). Invasive fungal infections are commonly treated with antifungal drugs such as azoles, polyenes, and echinocandins; however, their efficacy… read more here.

Keywords: cot 832; shionogi; polyene; antifungal activity ... See more keywords

P-1100. Activity of Cefiderocol and Comparator Agents Against Global Isolates of Stenotrophomonas maltophilia from the SENTRY Antimicrobial Surveillance Program (2020–2023)

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recommendations! Published in 2025 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae631.1288

Abstract: Abstract Background Stenotrophomonas maltophilia is a ubiquitous multidrug-resistant opportunistic pathogen. Infections caused by S. maltophilia have limited antibiotics treatment options due to the intrinsic resistant mechanisms such as the production of chromosomal L1 metallo-type carbapenemase… read more here.

Keywords: employee; shionogi; cefiderocol; comparator agents ... See more keywords

P-1472. Cefiderocol Remains Highly Active Against Carbapenemase-Producing Enterobacterales

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recommendations! Published in 2025 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae631.1642

Abstract: Abstract Background Carbapenem-resistance in Enterobacterales is mediated by the acquisition of β-lactamases, including serine carbapenemases (KPC and OXA-48) and metallo-β-lactamases (NDM, IMP and VIM). Cefiderocol (CFDC) is a siderophore conjugated cephalosporin with good stability against… read more here.

Keywords: cfdc; shionogi; carbapenemase producing; carbapenemase ... See more keywords