Activity- and sleep-dependent regulation of tonic inhibition by Shisa7
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108899
Abstract: SUMMARY Tonic inhibition mediated by extrasynaptic γ-aminobutyric acid type A receptors (GABAARs) critically regulates neuronal excitability and brain function. However, the mechanisms regulating tonic inhibition remain poorly understood. Here, we report that Shisa7 is critical… read more here.
Keywords: tonic inhibition; regulation tonic; inhibition; dependent regulation ... See more keywords
Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions
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DOI: 10.1126/science.aax5719
Abstract: Fine control of brain GABAA receptors GABAA (γ-aminobutyric acid type A) receptors are ligand-gated anion channels that mediate fast inhibitory transmission in the mammalian brain. Han et al. investigated if a protein called SHISA7 was… read more here.
Keywords: gabaa receptor; pharmacology; gabaa receptors; receptor ... See more keywords
Identification and Analysis of BCAS4/hsa-miR-185-5p/SHISA7 Competing Endogenous RNA Axis in Late-Onset Alzheimer’s Disease Using Bioinformatic and Experimental Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.812169
Abstract: Alzheimer’s disease (AD) is a heterogeneous degenerative brain disorder with a rising prevalence worldwide. SHISA7 (CKAMP59) has emerged as one of the most intriguing new members of the SHISA family, in that, unlike other CKAMP… read more here.
Keywords: shisa7; bcas4; expression; pathology ... See more keywords