Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail
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DOI: 10.1126/scitranslmed.aao4235
Abstract: A combination of HIV-1–specific broadly neutralizing antibodies is necessary to protect rhesus monkeys against a mixed SHIV challenge. Swatting away a swarm Monoclonal antibodies are being tested as therapy for many infections, including HIV. However,… read more here.
Keywords: mixed shiv; challenge; shiv challenge; antibody ... See more keywords
Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge
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DOI: 10.3390/vaccines13030231
Abstract: Background: The RV144 trial in Thailand is the only HIV-1 vaccine efficacy trial to date to demonstrate any efficacy. Genetic signatures suggested that antibodies targeting the variable loop 2 (V2) of the HIV-1 envelope played… read more here.
Keywords: hiv; subtype; shiv challenge; challenge ... See more keywords