Probiotic therapy during vaccination alters antibody response to SHIV infection but not to commensals.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0123
Abstract: The induction of robust circulating antibody titers is a key goal of HIV-1 vaccination. Probiotic supplementation is an established strategy to enhance microbiota and boost antibody responses to vaccines. A recent study tested whether oral… read more here.
Keywords: supplementation; vaccination; infection; shiv infection ... See more keywords
Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007776
Abstract: VRC01 protects macaques from vaginal SHIV infection after a single high-dose challenge. Infusion of a simianized anti-α4β7 mAb (Rh-α4β7) just prior to, and during repeated vaginal exposures to SIVmac251 partially protected macaques from vaginal SIV… read more here.
Keywords: infection vrc01; shiv infection; infection; delayed vaginal ... See more keywords
Functional MAIT Cells Are Associated With Reduced Simian–Human Immunodeficiency Virus Infection
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.03053
Abstract: Mucosa-associated invariant T (MAIT) cells are recently characterized as a novel subset of innate-like T cells that recognize microbial metabolites as presented by the MHC-1b-related protein MR1. The significance of MAIT cells in anti-bacterial defense… read more here.
Keywords: mait cells; shiv infection; mait; blood ... See more keywords