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Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches.

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Published in 2017 at "Birth defects research"

DOI: 10.1002/bdra.23623

Abstract: BACKGROUND Neural tube defects (NTDs) are caused by the failure of neural tube formation which occurs during early embryonic development. NTDs are the most severe and leading cause of fetal mortality. Serine hydroxymethyl transferase (SHMT1)… read more here.

Keywords: shmt1; case; neural tube; family based ... See more keywords