The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14617
Abstract: Upon heat shock, activated heat shock transcription factor 1 (HSF1) binds to the heat shock response elements (HSEs) in the promoters of mammalian heat shock protein (HSP)-encoding genes and recruits the preinitiation complex and coactivators,… read more here.
Keywords: hsf1 condensates; heat; shock response; heat shock ... See more keywords
Induction of the heat shock response in Arabidopsis by chlorinated 1,4-naphthoquinones
Sign Up to like & getrecommendations! Published in 2019 at "Plant Growth Regulation"
DOI: 10.1007/s10725-019-00477-3
Abstract: It is known that some plants produce 1,4-naphthoquinones (1,4NQs) to inhibit the growth of other plants as allelochemicals. Here, we report that a chlorinated 1,4NQ enhanced the heat tolerance of Arabidopsis, and this enhancement was… read more here.
Keywords: induction heat; heat shock; heat; shock response ... See more keywords
Versatile biomimetic cantharidin-tellurium nanoparticles enhance photothermal therapy by inhibiting the heat shock response for combined tumor therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.03.028
Abstract: The heat shock response (HSR) induced by photothermal therapy (PTT), which can cause tumor cells to resist apoptosis, has increasingly attracted the attention of researchers. Synergistic treatment of tumors using multiple means to improve therapeutic… read more here.
Keywords: versatile biomimetic; heat shock; therapy; shock response ... See more keywords
Shock response prediction of the typical structure in spacecraft based on the hybrid modeling techniques
Sign Up to like & getrecommendations! Published in 2019 at "Aerospace Science and Technology"
DOI: 10.1016/j.ast.2019.04.018
Abstract: Abstract In order to solve the failure of traditional methods in the response prediction for the complex spacecraft under the wide frequency shock load, this paper provides the FE-SEA (Finite Element-Statistical Energy Analysis) hybrid modeling… read more here.
Keywords: typical structure; hybrid modeling; structure; shock response ... See more keywords
Stepwise construction of a metabolic network in Event-B: The heat shock response
Sign Up to like & getrecommendations! Published in 2017 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2017.09.021
Abstract: There is a high interest in constructing large, detailed computational models for biological processes. This is often done by putting together existing submodels and adding to them extra details/knowledge. The result of such approaches is… read more here.
Keywords: heat shock; event; shock response;
Thermal shock response via weakly coupled peridynamic thermo-mechanics
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Solids and Structures"
DOI: 10.1016/j.ijsolstr.2017.09.010
Abstract: Abstract A 3D peridynamic formulation of the thermo-mechanical problem allows to efficiently simulate the occurrence and propagation of cracks due to extreme thermal loading. The model is weakly coupled since no internal heat generation due… read more here.
Keywords: thermo; thermal shock; shock response; mechanics ... See more keywords
Hsf1 on a leash - Controlling the heat shock response by chaperone titration.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112246
Abstract: Heat shock factor 1 (Hsf1) is an ancient transcription factor that monitors protein homeostasis (proteostasis) and counteracts disturbances by triggering a transcriptional programme known as the heat shock response (HSR). The HSR is transiently activated… read more here.
Keywords: heat shock; shock response; chaperone; hsf1 ... See more keywords
The heat shock response and humoral immune response are mutually antagonistic in honey bees
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09159-4
Abstract: The honey bee is of paramount importance to humans in both agricultural and ecological settings. Honey bee colonies have suffered from increased attrition in recent years, stemming from complex interacting stresses. Defining common cellular stress… read more here.
Keywords: response; heat shock; mutually antagonistic; shock response ... See more keywords
The cellular heat shock response monitored by chemical exchange saturation transfer MRI
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68022-1
Abstract: CEST-MRI of the rNOE signal has been demonstrated in vitro to be closely linked to the protein conformational state. As the detectability of denaturation and aggregation processes on a physiologically relevant scale in living organisms… read more here.
Keywords: heat shock; mri; heat; shock response ... See more keywords
Reproductive potential does not cause loss of heat shock response performance in honey bees
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74456-4
Abstract: In other species characterized to date, aging, as a function of reproductive potential, results in the breakdown of proteaostasis and a decreased capacity to mount responses by the heat shock response (HSR) and other proteostatic… read more here.
Keywords: maintenance; reproductive potential; heat shock; shock response ... See more keywords
Shock response of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX): The C-N bond scission studied by molecular dynamics simulations
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Physics"
DOI: 10.1063/1.5005804
Abstract: The shock response has a great influence on the design, synthesis, and application of energetic materials in both industrial and military areas. Therefore, the initial decomposition mechanism of bond scission at the atomistic level of… read more here.
Keywords: molecular dynamics; bond; rdx; bond scission ... See more keywords