Vericiguat in Combination with Short‐Acting Nitroglycerin in Patients With Chronic Coronary Syndromes: The Randomized, Phase Ib, VENICE Study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2574
Abstract: Vericiguat is a soluble guanylate cyclase stimulator indicated to reduce the risk of cardiovascular death and heart failure (HF) hospitalization in adults with symptomatic chronic HF and ejection fraction less than 45%. Guidelines recommend short‐acting… read more here.
Keywords: patients chronic; vericiguat; coronary syndromes; chronic coronary ... See more keywords
Electronic health record (EHR) based postmarketing surveillance of adverse events associated with pediatric off‐label medication use: A case study of short‐acting beta‐2 agonists and arrhythmias
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4562
Abstract: Use electronic health record (EHR) data to (1) estimate the risk of arrhythmia associated with inhaled short‐acting beta‐2 agonists (SABA) in pediatric patients and (2) determine whether risk varied by on‐label versus off‐label prescribing. read more here.
Keywords: acting beta; beta agonists; short acting; electronic health ... See more keywords
Discovery of Potent, Selective, and Short-Acting Peptidic V2 Receptor Agonists.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00132
Abstract: The vasopressin analogue desmopressin (desamino-d-arginine8 vasopressin, dDAVP, 1) is a potent vasopressin 2 (V2) receptor (V2R) agonist approved in many countries for the treatment of diabetes insipidus, primary nocturnal enuresis, nocturia, and coagulation disorders. Since… read more here.
Keywords: potent selective; selective short; acting peptidic; receptor ... See more keywords
Development of a potential opioid misuse measure from administrative dispensing data and contrasting opioid misuse among individuals on long-term tramadol, long-term short-acting hydrocodone or long-term short-acting oxycodone therapy in Arkansas
Sign Up to like & getrecommendations! Published in 2022 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2022.2112874
Abstract: Abstract Objective This study sought to: (1) construct and validate a composite potential opioid misuse score; and (2) compare potential opioid misuse among individuals prescribed long-term therapy on tramadol, short-acting hydrocodone or short-acting oxycodone. Methods… read more here.
Keywords: long term; opioid misuse; term; short acting ... See more keywords
Overprescription of short-acting β2-agonists is associated with poor asthma symptom control: results from five Middle Eastern countries included in the SABINA International (III) study
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2022.2099841
Abstract: ABSTRACT Background Although short-acting β2-agonist (SABA) overuse is associated with poor treatment outcomes, data on SABA use in the Middle East are lacking. Research design and methods In this cross-sectional study in patients (aged ≥12… read more here.
Keywords: saba; overprescription; saba prescriptions; short acting ... See more keywords
Understanding reliever overuse in patients purchasing over-the-counter short-acting beta2 agonists: an Australian community pharmacy-based survey
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Open"
DOI: 10.1136/bmjopen-2019-028995
Abstract: Objectives Overuse of asthma relievers is associated with significant adverse consequences. This study aimed to better understand the population purchasing and using short-acting beta agonists (SABA) over the counter (OTC); and compare the demographic, clinical… read more here.
Keywords: saba overusers; pharmacy; community pharmacy; asthma ... See more keywords
S137 Short-acting and long-acting β2-agonists upregulate asthma-relevant pro-inflammatory mediators in human airway epithelial cells while short-acting muscarinic antagonists do not
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thorax-2019-btsabstracts2019.143
Abstract: Introduction and objectives Despite their undoubted benefits, increased mortality is associated with overuse of short-acting β2-agonists (SABAs) and with using long-acting β2-agonists (LABAs) in the absence of inhaled corticosteroids (ICS). Mechanisms underlying these adverse effects… read more here.
Keywords: asthma relevant; short acting; epithelial cells; significant induction ... See more keywords
It is time to end our love affair with short-acting β2-agonists in asthma? Yes
Sign Up to like & getrecommendations! Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00555-2022
Abstract: I read with interest the editorial by Crooks and Faruqi [1]. I agree with almost all of the concepts; however, given my experience, I must question why the scientific community does not take a drastic… read more here.
Keywords: time; time end; acting agonists; love affair ... See more keywords
Short-acting β2-agonists and exacerbations in children with asthma in England: SABINA Junior
Sign Up to like & getrecommendations! Published in 2023 at "ERJ Open Research"
DOI: 10.1183/23120541.00571-2022
Abstract: Background Prescription of three or more short-acting β2-agonist (SABA) canisters per year in adult and adolescent asthma populations is associated with a risk of severe exacerbations; however, evidence in children aged 30% of patients across… read more here.
Keywords: canisters per; short acting; children asthma; saba canisters ... See more keywords
Short-acting β2-agonists (SABA) bronchodilator sales and outdoor mould in central France
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Translational Allergy"
DOI: 10.1186/s13601-019-0296-1
Abstract: BackgroundTemporal ecological studies have shown that outdoor moulds are associated with severe asthma exacerbations, as emergency department visits or hospitalisations. The aim of this was to assess the associations between daily sales of short-acting β2-agonists… read more here.
Keywords: central france; agonists saba; acting agonists; short acting ... See more keywords
The Changing Epidemiology of Adrenal Insufficiency: Iatrogenic Factors Predominate
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvad017
Abstract: Abstract Context Adrenal insufficiency (AI)-related morbidity persists despite efforts to minimize its effect. Reasons for this are unknown and warrant examination. Objective This work aimed to investigate trends in AI hospitalizations and glucocorticoid (GC) replacement… read more here.
Keywords: admission rates; short acting; adrenal insufficiency; admission ... See more keywords