Synthesis and short DNA in situ loading and delivery of 4 nm-aperture flexible organic frameworks
Sign Up to like & getrecommendations! Published in 2021 at "Materials Chemistry Frontiers"
DOI: 10.1039/d0qm00791a
Abstract: Water-soluble hydrazone-connected 3D flexible organic frameworks have been revealed to in situ load and deliver short DNA into normal and cancer cells. read more here.
Keywords: short dna; flexible organic; synthesis short; dna situ ... See more keywords
Thermal stabilisation of the short DNA duplexes by acridine-4-carboxamide derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac777
Abstract: Abstract The short oligodeoxynucleotide (ODN) probes are suitable for good discrimination of point mutations. However, the probes suffer from low melting temperatures. In this work, the strategy of using acridine-4-carboxamide intercalators to improve thermal stabilisation… read more here.
Keywords: short dna; point mutations; thermal stabilisation; stabilisation ... See more keywords
Anomalous Diffusion of Polyelectrolyte Segments on Supported Charged Lipid Bilayers
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DOI: 10.3390/e25050796
Abstract: This work provides mesoscale models for the anomalous diffusion of a polymer chain on a heterogeneous surface with rearranging randomly distributed adsorption sites. Both the “bead-spring” model and oxDNA model were simulated on supported lipid… read more here.
Keywords: diffusion; anomalous diffusion; short dna; lipid bilayers ... See more keywords