Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs
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DOI: 10.1073/pnas.2107111119
Abstract: Significance The innate immune system is a collection of essential frontline defenses against infectious pathogens such as viruses. Currently, however, we do not fully understand how one innate immune sensor of double-stranded RNA (dsRNA), oligoadenylate… read more here.
Keywords: short dsrnas; activate oas1; innate immune; oas1 ... See more keywords