Short and Modular Synthesis of Substituted 2-Aminopyrroles
Sign Up to like & getrecommendations! Published in 2021 at "Organic Letters"
DOI: 10.1021/acs.orglett.1c01345
Abstract: We herein describe a simple and metal-free domino methodology to synthesize 2-aminopyrroles from alkynyl vinyl hydrazides. The domino reaction involves a novel propargylic 3,4-diaza-Cope rearrangement and a tandem isomerization/5-exo-dig N-cyclization reaction. By using this approach,… read more here.
Keywords: methodology; modular synthesis; synthesis substituted; short modular ... See more keywords
Short and modular synthesis of tetraarylsalicylaldehydes.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc00738b
Abstract: In this study, we describe a novel strategy that allows the obtention of all 15 possible substitution geometries of perarylated salicylaldehydes with total control of the regioselectivity. This strategy entitles the formation of the salicylaldehyde… read more here.
Keywords: short modular; synthesis tetraarylsalicylaldehydes; modular synthesis;