Incorporating a Monofluoroalkene into the Backbones of Short Peptides: Evaluating the Impact on Local Hydrophobicity
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900082
Abstract: The local hydrophobicity of an amino acid residue in a peptide sequence can be determined by measuring the hydrophobicity index (φ0) by reversed‐phase (RP) HPLC. Herein, the impact on the local hydrophobicity of the replacement… read more here.
Keywords: monofluoroalkene backbones; impact local; short peptides; incorporating monofluoroalkene ... See more keywords
Synthesis of N,N‐dimethylaminopyrene‐modified short peptides for chemical photocatalysis
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DOI: 10.1002/psc.2966
Abstract: The synthesis of peptide‐based photocatalysts that use 1‐N,N‐dimethylaminopyrene as chromophore and their application in photocatalysis is reported. The copper(I)‐catalyzed alkyne‐azide cycloaddition was applied as key step to prepare the peptide–pyrene conjugates in quantitative yields for… read more here.
Keywords: peptide; synthesis dimethylaminopyrene; dimethylaminopyrene modified; short peptides ... See more keywords
Peptide oligomers from ultra-short peptides using sortase
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.02.005
Abstract: Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length. Cyclic peptides were the main products for peptides with more than 15aa.… read more here.
Keywords: oligomers ultra; short peptides; peptide oligomers; ultra short ... See more keywords
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
Sign Up to like & getrecommendations! Published in 2021 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2021.104391
Abstract: Nanostructures generated by self-assembly of peptides yield nanomaterials that have many therapeutic applications, including drug delivery and biomedical engineering, due to their low cytotoxicity and higher uptake by targeted cells owing to their high affinity… read more here.
Keywords: assembly sapdb; self assembly; nanostructures formed; short peptides ... See more keywords
Insulin chains as efficient fusion tags for prokaryotic expression of short peptides.
Sign Up to like & getrecommendations! Published in 2017 at "Protein expression and purification"
DOI: 10.1016/j.pep.2017.06.019
Abstract: Insulin chains are usually expressed in Escherichia coli as fusion proteins with different tags, including various low molecular weight peptide tags. The objective of this study was to determine if insulin chains could facilitate the… read more here.
Keywords: insulin chains; efficient fusion; expression; short peptides ... See more keywords
Whether short peptides are good candidates for future neuroprotective therapeutics?
Sign Up to like & getrecommendations! Published in 2021 at "Peptides"
DOI: 10.1016/j.peptides.2021.170528
Abstract: Neurodegenerative diseases are a broad group of largely debilitating, and ultimately terminal conditions resulting in progressive degeneration of different brain regions. The observed damages are associated with cell death, structural and functional deficits of neurons,… read more here.
Keywords: candidates future; good candidates; future neuroprotective; short peptides ... See more keywords
Game-changing alternatives to conventional fungicides: small RNAs and short peptides.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2021.07.003
Abstract: Fungicide use is one of the core elements of intensive agriculture because it is necessary to fight pathogens that would otherwise cause large production losses. Oomycete and fungal pathogens are kept under control using several… read more here.
Keywords: alternatives conventional; game changing; changing alternatives; short peptides ... See more keywords
Investigating the Short Peptidome Profile of Italian Dry-Cured Ham at Different Processing Times by High-Resolution Mass Spectrometry and Chemometrics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23063193
Abstract: Short peptides have been spiking interest owing to their significant contribution to the taste and functional properties of dry-cured ham. In this study, a suspect screening approach based on high-resolution mass spectrometry was employed for… read more here.
Keywords: high resolution; short peptides; cured ham; processing ... See more keywords
Role of the Guanidinium Groups in Ligand–Receptor Binding of Arginine-Containing Short Peptides to the Slow Sodium Channel: Quantitative Approach to Drug Design of Peptide Analgesics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810640
Abstract: Several arginine-containing short peptides have been shown by the patch-clamp method to effectively modulate the NaV1.8 channel activation gating system, which makes them promising candidates for the role of a novel analgesic medicinal substance. As… read more here.
Keywords: short peptides; ligand receptor; guanidinium groups; containing short ... See more keywords