Short RNA regulators: the past, the present, the future, and implications for precision medicine and health disparities.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2019.05.014
Abstract: We herein provide a brief review of the trajectory that the field of short RNA research followed in the last 25 years. We place emphasis on the unexpected discoveries and the ramifications of these discoveries… read more here.
Keywords: medicine; rna regulators; short rna; health disparities ... See more keywords
Optimization of Short RNA Aptamers for TNBC Cell Targeting
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073511
Abstract: Triple-negative breast cancer (TNBC) is an aggressive cancer with limited targeted therapies. RNA aptamers, suitably chemically modified, work for therapeutic purposes in the same way as antibodies. We recently generated 2′Fluoro-pyrimidines RNA-aptamers that act as… read more here.
Keywords: short rna; aptamers tnbc; tnbc cell; optimization short ... See more keywords