Isometric artifacts from polymerase chain reaction‐massively parallel sequencing analysis of short tandem repeat loci: An emerging issue from a new technology?
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202100143
Abstract: The recent introduction of polymerase chain reaction (PCR)‐massively parallel sequencing (MPS) technologies in forensics has changed the approach to allelic short tandem repeat (STR) typing because sequencing cloned PCR fragments enables alleles with identical molecular… read more here.
Keywords: chain reaction; polymerase chain; parallel sequencing; massively parallel ... See more keywords
Rapid multiplex DNA amplification on an inexpensive microdevice for human identification via short tandem repeat analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.04.051
Abstract: Forensic DNA analysis requires several steps, including DNA extraction, PCR amplification, and separation of PCR fragments. Intuitively, there are numerous situations where it would be beneficial to speed up the overall DNA analysis process; in… read more here.
Keywords: short tandem; dna; analysis; microdevice ... See more keywords
Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Human Genetics"
DOI: 10.1016/j.ajhg.2017.09.013
Abstract: Short tandem repeats (STRs) are hyper-mutable sequences in the human genome. They are often used in forensics and population genetics and are also the underlying cause of many genetic diseases. There are challenges associated with… read more here.
Keywords: short tandem; genetics; repeat; disease ... See more keywords
Short Tandem Repeats in plants: Genomic distribution and function prediction
Sign Up to like & getrecommendations! Published in 2021 at "Electronic Journal of Biotechnology"
DOI: 10.1016/j.ejbt.2020.12.003
Abstract: Abstract Background Short Tandem repeats (STRs) existed as popular elements in both eukaryotic and prokaryotic genomes. Results In this study, we analyzed the characteristics, distributions, and motif features of STRs within whole-genomes of 140 plant… read more here.
Keywords: short tandem; long strs; tandem repeats; repeats plants ... See more keywords
LEPStr: A database for Mycobacterium leprae short tandem repeats
Sign Up to like & getrecommendations! Published in 2020 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2020.100322
Abstract: Abstract Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to… read more here.
Keywords: short tandem; repeat; database; mycobacterium leprae ... See more keywords
Investigation of short tandem repeats in major depression using whole-genome sequencing data.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.02.046
Abstract: BACKGROUND Major depressive disorder (MDD) is a leading contributor to global disease burden. Recent studies have shown that genetic factors play significant roles in the susceptibility to this condition; however, the underlying genetic basis currently… read more here.
Keywords: whole genome; short tandem; genome sequencing; genome ... See more keywords
Forensic parameters and mutation analysis of 23 short tandem repeat (PowerPlex® Fusion System) loci in Fujian Han Chinese population.
Sign Up to like & getrecommendations! Published in 2019 at "Legal medicine"
DOI: 10.1016/j.legalmed.2019.01.005
Abstract: Kinship testing based on genetic markers has valuable practical applications. Short tandem repeat polymorphisms (STRPs) can have large number of alleles, and become the dominant marker for kinship identification. However, the high mutation rates affect… read more here.
Keywords: short tandem; tandem repeat; mutation; mutation rate ... See more keywords
Donor-Derived Neuroendocrine Carcinoma Transmission to Two Kidney Transplant Recipients Demonstrated by Short Tandem Repeat Analysis: A Case Report.
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2021.03.002
Abstract: Cancer transmission from a donor organ to a transplant recipient is a rare but not infrequently fatal event. We report a case of lung cancer transmission from a deceased donor to 2 kidney recipients. Approximately… read more here.
Keywords: short tandem; transmission; tandem repeat; donor ... See more keywords
Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors
Sign Up to like & getrecommendations! Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-018-0120-z
Abstract: Genome-wide association studies (GWAS) of complex, heritable, behavioral phenotypes have yielded an incomplete accounting of the genetic influences. The identified loci explain only a portion of the observed heritability, and few of the loci have… read more here.
Keywords: short tandem; receptor avpr1a; tandem repeats; arginine vasopressin ... See more keywords
Enhanced resistance to bacterial and oomycete pathogens by short tandem target mimic RNAs in tomato
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1814380116
Abstract: Significance Plants, like animals, have complex disease resistance systems in which receptors interact directly or indirectly with effectors of disease produced by pests and pathogens. To minimize the fitness cost of these systems to the… read more here.
Keywords: short tandem; disease resistance; target; mir482 2118 ... See more keywords
Error-Correcting Codes for Short Tandem Duplication and Edit Errors
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Information Theory"
DOI: 10.1109/tit.2021.3125724
Abstract: Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging… read more here.
Keywords: duplication; short tandem; tandem duplication; edit ... See more keywords