Quantitative Profiling of Lysosomal Lipidome by Shotgun Lipidomics.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6934-0_2
Abstract: Recent studies have illuminated novel roles of lysosomes that go far beyond simple catabolism and function in the coordination of cellular metabolism and signaling. Promising therapeutic strategies emerge from knowledge in the molecular mechanisms and… read more here.
Keywords: quantitative profiling; profiling lysosomal; metabolism; shotgun lipidomics ... See more keywords
Global Monitoring of the Mammalian Lipidome by Quantitative Shotgun Lipidomics.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6996-8_12
Abstract: The emerging field of lipidomics presents the systems biology approach to identify and quantify the full lipid repertoire of cells, tissues, and organisms. The importance of the lipidome is demonstrated by a number of biological… read more here.
Keywords: shotgun lipidomics; global monitoring; quantitative shotgun; biology ... See more keywords
Mass spectrometry-based shotgun lipidomics – a critical review from the technical point of view
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1252-y
Abstract: AbstractOver the past decade, mass spectrometry (MS)-based “shotgun lipidomics” has emerged as a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological system. The aim of this critical review is to… read more here.
Keywords: spectrometry based; shotgun lipidomics; mass spectrometry; based shotgun ... See more keywords
Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102115
Abstract: Summary Sentinel species are playing an indispensable role in monitoring environmental pollution in aquatic ecosystems. Many pollutants found in water prove to be endocrine disrupting chemicals that could cause disruptions in lipid homeostasis in aquatic… read more here.
Keywords: mass spectrometry; shotgun lipidomics; gammarus fossarum; composition ... See more keywords
Shotgun lipidomics combined targeted MRM reveals sphingolipid signatures of coronary artery disease.
Sign Up to like & getrecommendations! Published in 2022 at "Talanta"
DOI: 10.1016/j.talanta.2022.123475
Abstract: Sphingolipids (SPLs) are bioactive lipids that manifest structural diversity and complexity in eukaryotes. However, the distributions and functions of these molecules in mammalian tissues/cells have not been systematically investigated. Herein, we integrated shotgun lipidomics with… read more here.
Keywords: spl; shotgun lipidomics; coronary artery; spl molecules ... See more keywords
Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics
Sign Up to like & getrecommendations! Published in 2019 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2019.1698026
Abstract: Abstract This study aimed to identify potential lipid biomarkers in women with polycystic ovary syndrome (PCOS) and determine their predictive value for PCOS. Eighteen women with PCOS and 17 healthy controls were enrolled. A multi-dimensional… read more here.
Keywords: women polycystic; polycystic ovary; shotgun lipidomics; novel lipid ... See more keywords