H-ABC– and dystonia-causing TUBB4A mutations show distinct pathogenic effects
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abj9229
Abstract: Mutations in the brain-specific β-tubulin 4A (TUBB4A) gene cause a broad spectrum of diseases, ranging from dystonia (DYT-TUBB4A) to hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC). Currently, the mechanisms of how TUBB4A… read more here.
Keywords: causing tubb4a; mutations show; abc dystonia; dystonia causing ... See more keywords
Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization
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DOI: 10.3389/fimmu.2020.00152
Abstract: Macrophages play important roles in conditions ranging from host immune defense to tissue regeneration and polarize their functional phenotype accordingly. Next to differences in the use of L-arginine and the production of different cytokines, inflammatory… read more here.
Keywords: show distinct; metabolic reprogramming; distinct metabolic; metabolic signatures ... See more keywords
Human Papillary and Reticular Fibroblasts Show Distinct Functions on Tumor Behavior in 3D-Organotypic Cultures Mimicking Melanoma and HNSCC
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911651
Abstract: Human dermis can be morphologically divided into the upper papillary and lower reticular dermis. Previously, we demonstrated that papillary (PFs) and reticular (RFs) fibroblasts show distinct morphology and gene expression profiles. Moreover, they differently affect… read more here.
Keywords: cell; show distinct; rfs; hnscc ... See more keywords