Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
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DOI: 10.1371/journal.ppat.1008811
Abstract: Damage-associated molecular patterns (DAMPs) are endogenous molecules activating the immune system upon release from injured cells. Here we show that the IFI16 protein, once freely released in the extracellular milieu of chronically inflamed tissues, can… read more here.
Keywords: ifi16; toll like; inflammation; like receptor ... See more keywords