Neoadjuvant pembrolizumab shows promise
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-018-0131-y
Abstract: org/10.1200/JCO.18.01148 (2018) Neoadjuvant cisplatin-based chemotherapy followed by radical cystectomy (RC) is the standard-of-care approach for patients with muscle-invasive bladder cancer (MIBC); however, this approach is rarely used owing to poor tolerability. Now, new data from… read more here.
Keywords: chemotherapy; disease; pembrolizumab shows; neoadjuvant pembrolizumab ... See more keywords
Targeting the EGFR pathway shows promise for OA
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-021-00583-5
Abstract: 0123456789();: while enabling prolonged retention and high cartilage penetration. Similar to EGFR overactivation, intra-articular delivery of these TGFα-conjugated nanoparticles in the knees of mice attenuated the development of surgery-induced OA. “We are currently collaborating with… read more here.
Keywords: egfr pathway; rheumatology; pathway shows; shows promise ... See more keywords
Complex intensive treatment shows promise against a complex aggressive disease
Sign Up to like & getrecommendations! Published in 2019 at "Neurology"
DOI: 10.1212/wnl.0000000000008385
Abstract: Neuromyelitis optica (NMO) spectrum disorder (NMOSD) comprises a group of neuroinflammatory disorders characteristically affecting the optic nerves and the spinal cord. Previously known as Devic disease, NMO was considered a variant of multiple sclerosis (MS)… read more here.
Keywords: complex intensive; intensive treatment; shows promise; treatment shows ... See more keywords