OP0306 CD11C-SPECIFIC ABLATION OF SHP1 INDUCES AUTOIMMUNE SIALADENITIS SIMILAR TO SJÖGREN’S SYNDROME
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DOI: 10.1136/annrheumdis-2020-eular.1044
Abstract: Dendritic cells (DCs) play important roles in inducing immune response as well as maintaining immune tolerance. Src homology 2 domain-containing protein tyrosine phosphatase-1 (Shp1) is a negative regulator of signaling in hematopoietic cells and is… read more here.
Keywords: shp1; none declared; shp1 cko; salivary glands ... See more keywords