Engineered Extracellular Vesicles with SHP2 High Expression Promote Mitophagy for Alzheimer's Disease Treatment
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DOI: 10.1002/adma.202207107
Abstract: Mitochondrial dysfunction is a fundamental pathological feature of Alzheimer's disease (AD). However, toxicity and poor brain enrichment of existing mitophagy inducers limit their further applications. In this study, a platform for AD therapy is developed… read more here.
Keywords: extracellular vesicles; alzheimer disease; high expression; mitophagy ... See more keywords