Taurine reduces hyperactive behavior in SHR rats through upregulating the proportion of CD4+CD25+Foxp3+ regulatory T cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.03.032
Abstract: Abstract Attention deficit hyperactivity disorder (ADHD) is a most common mental illness in both children and adults. Our recent studies revealed that high-dose taurine improves hyperactivity in SHR rats by reducing mALFF signal and striatal… read more here.
Keywords: rats fed; shr rats; dose taurine; high dose ... See more keywords
20-Hydroxyecdysone attenuates cardiac remodeling in spontaneously hypertensive rats
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DOI: 10.1016/j.steroids.2017.08.004
Abstract: Background: Ecdysteroids, a group of steroid hormones found in insects and many plants, have been shown to prevent various changes in mammalian tissues after female sex hormone deprivation. Purpose: To examine whether an ecdysteroid, 20‐hydroxyecdysone… read more here.
Keywords: spontaneously hypertensive; hypertensive rats; blood pressure; shr rats ... See more keywords
Changes in plasma aldosterone and electrolytes levels, kidney epithelial sodium channel (ENaC) and blood pressure in normotensive WKY and hypertensive SHR rats following gonadectomy and chronic testosterone treatment
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DOI: 10.1016/j.steroids.2017.09.008
Abstract: HighlightsTestosterone causes MAP to increase in females.Testosterone induces decreased in aldosterone, sodium (Na+) and osmolality levels in females.Expression and distribution of &agr;, &bgr; and &ggr;‐ENaC in kidneys in females decreased under testosterone influence.Orchidectomy decreases MAP… read more here.
Keywords: shr rats; plasma aldosterone; enac; testosterone ... See more keywords
A9052 Effect of Renal Denervation on Hypothalamus p38MAPK and p65NFkB Signal Pathway in SHR Rats
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DOI: 10.1097/01.hjh.0000548209.67742.ad
Abstract: Objectives: This study is to observe the change of hypothalamic AngII, AT1R, p38MAPK and p65NF&kgr;B before and after renal denervation on spontaneously hypertensive rats, to observe the effect of renal denervation on MAPK and NFKB… read more here.
Keywords: renal denervation; group; shr rats; p38mapk ... See more keywords
TOTUM-854 REDUCTION OF BLOOD PRESSURE IS ASSOCIATED WITH AN ANTI-OXIDATIVE EFFECT IN SHR RATS
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837824.82488.44
Abstract: Objective: Arterial Hypertension (AHT) is a major cause of premature death worldwide. We have developed Totum-854 (T-854), a polyphenol-rich botanical composition to reduce the risk of developing AHT. We assessed the acute and chronic effects… read more here.
Keywords: reduction; pressure; blood pressure; shr rats ... See more keywords
Comparative analysis of autonomic effects of ketamine-xylazine in normotensive and hypertensive rats
Sign Up to like & getrecommendations! Published in 2025 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x2025e14598
Abstract: This study aimed to evaluate the effects of the ketamine-xylazine (KX) anesthetic mixture on autonomic and cardiovascular functions in normotensive rats (Wistar) and spontaneously hypertensive rats (SHR), using both spectral and symbolic analyses. Male Wistar… read more here.
Keywords: ketamine xylazine; effects ketamine; analysis; shr rats ... See more keywords
Impact of low-to moderate-intensity exercise training on the mRNA expression of purine receptors across various vessels in SHR
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DOI: 10.3233/ch-242366
Abstract: OBJECTIVE: In this study, we developed an exercise training protocol for assessing both blood pressure dynamics and mRNA expression levels of purine receptors in various vascular tissues during physical activity. The objective is to assess… read more here.
Keywords: shr rats; mrna expression; exercise training; exercise ... See more keywords
Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.811371
Abstract: Cerebral amyloid angiopathy (CAA), a common comorbidity of Alzheimer’s disease (AD), is a cerebral small vessel disease (CSVD) characterized by deposition of fibrillar amyloid β (Aβ) in blood vessels of the brain and promotes neuroinflammation… read more here.
Keywords: rtg shr; amyloid; bigenic rtg; shr ... See more keywords
Dipeptide IF and Exercise Training Attenuate Hypertension in SHR Rats by Inhibiting Fibrosis and Hypertrophy and Activating AMPKα1, SIRT1, and PGC1α
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158167
Abstract: Bioactive peptides are physiologically active peptides produced from proteins by gastrointestinal digestion, fermentation, or hydrolysis by proteolytic enzymes. Bioactive peptides are resorbed in their whole form and have a preventive effect against various disease conditions,… read more here.
Keywords: fibrosis hypertrophy; exercise training; shr; exercise ... See more keywords