Silencing TLR4 using an ultrasound-targeted microbubble destruction-based shRNA system reduces ischemia-induced seizures in hyperglycemic rats
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DOI: 10.1515/biol-2022-0526
Abstract: Abstract The toll-like receptor 4 (TLR4) pathway is involved in seizures. We investigated whether ultrasound-targeted microbubble destruction (UTMD)-mediated delivery of short hairpin RNA (shRNA) targeting the TLR4 gene (shRNA-TLR4) can reduce ischemia-induced seizures in rats… read more here.
Keywords: shrna tlr4; shrna; ischemia induced; ultrasound targeted ... See more keywords