Emulsified isoflurane induces release of cytochrome C in human neuroblastoma SHSY-5Y cells via JNK (c-Jun N-terminal kinases) signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2017.12.001
Abstract: A large number of studies have demonstrated that inhalation anesthetic isoflurane induced neural cell death by apoptosis in various cell and animal models. Emulsified isoflurane (EIso) is a new type of intravenous preparation of isoflurane… read more here.
Keywords: jnk; shsy cells; human neuroblastoma; neuroblastoma shsy ... See more keywords
Isocyanate induces cytotoxicity via activation of phosphorylated alpha synuclein protein, nitrosative stress, and apoptotic pathway in Parkinson’s Disease model-SHSY-5Y cells
Sign Up to like & getrecommendations! Published in 2023 at "Neurological Research"
DOI: 10.1080/01616412.2023.2181919
Abstract: ABSTRACT Background Neurotoxic disorders account for a significant portion of the diseases that influence the worldwide disease burden. Parkinson’s disease is one such disease that is linked with environmental toxin exposure. Isocyanates are a highly… read more here.
Keywords: disease; shsy; shsy cells; nitrosative stress ... See more keywords
Modulation of IGF1R Signaling Pathway by GIGYF1 in High Glucose-Induced SHSY-5Y Cells.
Sign Up to like & getrecommendations! Published in 2018 at "DNA and cell biology"
DOI: 10.1089/dna.2018.4336
Abstract: Grb10 (growth factor receptor-bound protein 10)-interacting GYF protein 1 (GIGYF1) can modulate insulin-like growth factor 1 receptor (IGF1R) signaling pathway, which plays an important role in regulating diabetes-associated cognitive impairment, by linking to Grb10 adapter.… read more here.
Keywords: shsy cells; signaling pathway; high glucose; igf1r signaling ... See more keywords
Monomethyl lithospermate alleviates ischemic stroke injury in middle cerebral artery occlusion mice in vivo and protects oxygen glucose deprivation/reoxygenation induced SHSY-5Y cells in vitro via activation of PI3K/Akt signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1024439
Abstract: Stroke is a fatal neurological disease, which seriously threatens human health and life. Ischemic stroke (IS) is the most common type of stroke in clinic. Its pathogenesis is very complex, mainly caused by nerve damage… read more here.
Keywords: pi3k akt; shsy cells; monomethyl lithospermate; induced shsy ... See more keywords
PS-NPs Induced Neurotoxic Effects in SHSY-5Y Cells via Autophagy Activation and Mitochondrial Dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12070952
Abstract: Polystyrene nanoparticles (PS-NPs) are organic pollutants that are widely detected in the environment and organisms, posing potential threats to both ecosystems and human health. PS-NPs have been proven to penetrate the blood–brain barrier and increase… read more here.
Keywords: via autophagy; activation mitochondrial; autophagy activation; shsy cells ... See more keywords