Securin-independent regulation of separase by checkpoint-induced shugoshin–MAD2
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DOI: 10.1038/s41586-020-2182-3
Abstract: Separation of eukaryotic sister chromatids during the cell cycle is timed by the spindle assembly checkpoint (SAC) and ultimately triggered when separase cleaves cohesion-mediating cohesin 1 – 3 . Silencing of the SAC during metaphase… read more here.
Keywords: separase; securin; shugoshin mad2; checkpoint ... See more keywords