Shunt products of aminoansamycins from aas1 overexpressed mutant strain of Streptomyces sp. S35.
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DOI: 10.1016/s1875-5364(20)60039-5
Abstract: Constitutively expression of the pathway-specific activators is an effective method to activate silent gene clusters and improve natural product production. In this study, nine shunt products of aminoansamycins (1-9) were identified from a recombinant mutant… read more here.
Keywords: streptomyces s35; products aminoansamycins; mutant strain; shunt products ... See more keywords
Isolation and Biological Activity of 9-epiTetrodotoxin and Isolation of Tb-242B, Possible Biosynthetic Shunt Products of Tetrodotoxin from Pufferfish.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00588
Abstract: Tetrodotoxin (TTX, 1) is a potent voltage-gated sodium channel blocker detected in certain marine and terrestrial organisms. We report here a new TTX analogue, 9-epiTTX (2), and a TTX-related compound, Tb-242B (4), isolated from the… read more here.
Keywords: possible biosynthetic; biological activity; ttx; isolation ... See more keywords