The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma
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DOI: 10.3390/biomedicines10030659
Abstract: Si306, a pyrazolo[3,4-d]pyrimidine derivative recently identified as promising anticancer agent, has shown favorable in vitro and in vivo activity profile against neuroblastoma (NB) models by acting as a competitive inhibitor of c-Src tyrosine kinase. Nevertheless,… read more here.
Keywords: gd2; si306 encapsulated; pyrimidine derivative; neuroblastoma ... See more keywords
Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells
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DOI: 10.3390/pharmaceutics14071399
Abstract: Glioblastoma (GBM) is the most common adult brain tumor and, although many efforts have been made to find valid therapies, the onset of resistance is the main cause of recurrence. Therefore, it is crucial to… read more here.
Keywords: glioblastoma; effect; si306; anti survival ... See more keywords