Simple and practical sialoglycan encoding system reveals vast diversity in nature and identifies a universal sialoglycan-recognizing probe derived from AB5 toxin B subunits.
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DOI: 10.1093/glycob/cwac057
Abstract: Vertebrate sialic acids (Sias) display much diversity in modifications, linkages and underlying glycans. Slide microarrays allow high-throughput explorations of sialoglycan-protein interactions. A microarray presenting ~150 structurally-defined sialyltrisaccharides with various Sias linkages and modifications still poses… read more here.
Keywords: sialoglycan recognizing; diversity; encoding system; ab5 toxin ... See more keywords